Nicotinamide riboside is a very well-known drug that is being commercially traded all over the world. It’s a kind of drug from nootropic group of drugs which are known as “smart drugs.” In 1964 it was synthesised at the Belgian pharmaceutical company UCB and till now it’s very famous drug among students as a memory booster. The medical term nootropic has come from a Greek word which means waking up of your brain. It also helps to recover various diseases and is widely used for the treatment of aging, Alzheimer’s disease, clotting and coagulation of blood, vasospastic disorders, alcoholism, depression and anxiety, stroke, ischemia, schizophrenia, craniocerebral trauma and as a preventive for breath-holding spells. It is a piracetam drug which has many brand names for trading in different countries. In Argentina Nicotinamide riboside is traded as a piracetam drug.
The mechanism of its action is actually not fully understood. It has been observed that N(r) influences the functions of neuron and as a stimulant it also influence cognitive and vascular functions. It makes the brain to increase blood flow and more oxygen consumption due to enhanced brain activities. It also boosts the memory and learning process by affecting NMDA glutamate receptors of our brain. This drug also helps to increase permeability of mitochondria during Krebs’s cycle of our brain. As it increases the synthesis of cytochrome b5 and which actually is a part of electron carrier system in mitochondria. [Read more...]